Alpha‐kinase 1 (ALPK1) agonist DF‐006 demonstrates potent efficacy in mouse and primary human hepatocyte (PHH) models of hepatitis B
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DOI: 10.1002/hep.32614
Abstract: Background and Aims: In the treatment of chronic hepatitis B (CHB) infection, stimulation of innate immunity may lead to hepatitis B virus (HBV) cure. Alpha‐kinase 1 (ALPK1) is a pattern recognition receptor (PRR) that activates… read more here.
Keywords: phh; hbv; mouse; efficacy ... See more keywords
Thrombocytopenia: is it a prognostic factor for development of post-hemorrhagic hydrocephalus in neonates?
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DOI: 10.1007/s00381-020-04790-5
Abstract: Purpose Post-hemorrhagic hydrocephalus (PHH) is a rare but serious complication among premature babies in the neonatal intensive care unit. The causes of PHH are still not entirely understood, and its prevention and treatment are controversial.… read more here.
Keywords: post hemorrhagic; hemorrhagic hydrocephalus; phh;
Conditions for maintenance of hepatocyte differentiation and function in 3D cultures
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DOI: 10.1016/j.isci.2021.103235
Abstract: Summary Spheroid cultures of primary human hepatocytes (PHH) are used in studies of hepatic drug metabolism and toxicity. The cultures are maintained under different conditions, with possible confounding results. We performed an in-depth analysis of… read more here.
Keywords: conditions maintenance; differentiation function; maintenance hepatocyte; phh ... See more keywords
Preliminary Experience Suggests the Addition of Choroid Plexus Cauterization to Functional Hemispherectomy May Reduce Posthemispherectomy Hydrocephalus
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DOI: 10.1227/neu.0000000000002193
Abstract: BACKGROUND: Cerebral hemispherectomy can effectively treat unihemispheric epilepsy. However, posthemispherectomy hydrocephalus (PHH), a serious life-long complication, remains prevalent, requiring careful considerations in technique selection and postoperative management. In 2016, we began incorporating open choroid plexus… read more here.
Keywords: hemispherectomy; phh; cpc; choroid plexus ... See more keywords
Outcomes of patients with post-hepatectomy hypophosphatemia: A narrative review
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DOI: 10.4254/wjh.v14.i8.1550
Abstract: Phosphate is an essential electrolyte for proper mineralisation of bone, buffering of urine, and diverse cellular actions. Hypophosphatemia (HP) is a clinical spectrum which range from asymptomatic to severe complications such as neuromuscular and pulmonary… read more here.
Keywords: outcomes patients; phh; review; post hepatectomy ... See more keywords