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   Articles with "phillyrin" as a keyword



Research on Preparation Technology and Performance of Phillyrin Self-Microemulsion

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recommendations! Published in 2025 at "ACS Omega"

DOI: 10.1021/acsomega.5c05684

Abstract: Phillyrin has many effects, such as reducing blood lipids, anti-inflammatory properties, lowering blood pressure, and decreasing tyrosinase activity. However, the bioavailability of phillyrin with oral administration is very low due to its poor water solubility.… read more here.

Keywords: self microemulsion; research preparation; phillyrin; phillyrin self ... See more keywords

Phillyrin prevents calcium oxalate kidney stones through the PPARγ signaling pathway

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recommendations! Published in 2025 at "Renal Failure"

DOI: 10.1080/0886022x.2025.2486559

Abstract: Abstract Background Nephrolithiasis is a significant health issue causing pain, hypertension, and chronic kidney disease. Phillyrin, a bioactive compound from Forsythia suspensa, may offer therapeutic benefits against these conditions. The study was focused on phillyrin… read more here.

Keywords: calcium oxalate; phillyrin; ppar signaling; kidney stones ... See more keywords

Phillyrin reduces ROS production to alleviate the progression of intervertebral disc degeneration by inhibiting NF-κB pathway

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recommendations! Published in 2024 at "Journal of Orthopaedic Surgery and Research"

DOI: 10.1186/s13018-024-04695-y

Abstract: Intervertebral disc degeneration (IDD) is an increasingly important cause of low back pain (LBP) that results in substantial health and economic burdens. Inflammatory pathway activation and the production of reactive oxygen species (ROS) play vital… read more here.

Keywords: disc degeneration; intervertebral disc; phillyrin; idd ... See more keywords

Phillyrin restores metabolic disorders in mice fed with high-fat diet through inhibition of interleukin-6-mediated basal lipolysis

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recommendations! Published in 2022 at "Frontiers in Nutrition"

DOI: 10.3389/fnut.2022.956218

Abstract: The function of white adipose tissue as an energy reservoir is impaired in obesity, leading to lipid spillover and ectopic lipid deposition. Adipose tissue inflammation can reduce the efficacy of lipid storage in adipocytes by… read more here.

Keywords: obesity; adipose tissue; basal lipolysis; phillyrin ... See more keywords