LAUSR

PHLPP1 mediates melanoma metastasis suppression through repressing AKT2 activation

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0 Published in 2018 at "Oncogene"

DOI: 10.1038/s41388-017-0061-7

Abstract: PI3K/AKT pathway activation is thought to be a driving force in metastatic melanomas. Members of the pleckstrin homology (PH) domain leucine-rich repeat protein Ser/Thr specific phosphatase family (PHLPP1 and PHLPP2) can regulate AKT activation. By… read more here.

Keywords: phlpp1; phlpp1 mediates; metastasis; activation ... See more keywords