Articles with "phmb" as a keyword



Antibacterial efficacy of chitosan- and poly(hexamethylene biguanide)-immobilized nanofiber membrane.

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Published in 2020 at "International journal of biological macromolecules"

DOI: 10.1016/j.ijbiomac.2020.03.127

Abstract: In this study, polyacrylonitrile (PAN) nanofiber membrane was prepared by an electrospinning technique. After alkaline hydrolysis, the ion-exchange nanofiber membrane (P-COOH) was grafted with chitosan molecules to form a chitosan-modified nanofiber membrane (P-COOH-CS). Poly(hexamethylene biguanide)… read more here.

Keywords: cooh; cooh phmb; nanofiber membrane; phmb ... See more keywords

Synthesis and evaluation of chitosan-PHMB conjugates as efficient antibacterial agents

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Published in 2025 at "International Journal of Polymeric Materials and Polymeric Biomaterials"

DOI: 10.1080/00914037.2025.2553760

Abstract: Abstract Antimicrobial resistance has emerged as a silent pandemic affecting both humans and livestock. This resistance arises as microbes develop means of evading antibiotics, such as efflux systems and drug target modifications. Consequently, there is… read more here.

Keywords: chitosan phmb; phmb; synthesis evaluation; antimicrobial agents ... See more keywords

The Effect of Antiamoebic Agents on Viability, Proliferation and Migration of Human Epithelial Cells, Keratocytes and Endothelial Cells, In Vitro

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Published in 2018 at "Current Eye Research"

DOI: 10.1080/02713683.2018.1447674

Abstract: ABSTRACT Purpose: To analyze the effect of diamidines (hexamidine-diisethionat (HD), propamidin-isethionate (PD), dibromopropamidine-diisethionat (DD)), and biguanides (polyhexamethylen biguanid (PHMB), chlorhexidine (CH)) on human corneal epithelial cell, keratocyte and endothelial cell viability, proliferation, and migration, in… read more here.

Keywords: proliferation migration; auc comparing; viability; proliferation ... See more keywords

Polihexanide (PHMB) 0.08% versus currently used treatments for Acanthamoeba keratitis: indirect treatment comparisons

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Published in 2025 at "BMJ Open Ophthalmology"

DOI: 10.1136/bmjophth-2024-002082

Abstract: Background/aims Acanthamoeba keratitis is a rare, severe corneal infection. Until the recent approval of polihexanide (PHMB) 0.08% by the European Medicines Agency, there were no licensed medical therapies and current treatments relied on off-label or… read more here.

Keywords: treatment; currently used; phmb; indirect treatment ... See more keywords

Dual Crosslinked Ion-Based Bacterial Cellulose Composite Hydrogel Containing Polyhexamethylene Biguanide

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Published in 2022 at "Membranes"

DOI: 10.3390/membranes12090825

Abstract: Composite bacterial cellulose (BC) based hydrogel with alginate (A) or pectin (P) or alginate and pectin was fabricated via a physical crosslinking technique using calcium chloride (CaCl2) solution and incorporated with polyhexamethylene biguanide (PHMB) as… read more here.

Keywords: dual crosslinked; bacterial cellulose; hydrogel; phmb hydrogel ... See more keywords