Metabolomic study on bleomycin and polyhexamethylene guanidine phosphate-induced pulmonary fibrosis mice models
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DOI: 10.1007/s11306-019-1574-6
Abstract: Polyhexamethylene guanidine phosphate (PHMG) has been used as a disinfectant and biocide, and was known to be harmless and non-toxic. However, in 2011, PHMG used as a humidifier disinfectant was reported to be associated with… read more here.
Keywords: guanidine phosphate; fibrosis; induced pulmonary; polyhexamethylene guanidine ... See more keywords
Disruption of Membrane Integrity as a Molecular Initiating Event Determines the Toxicity of Polyhexamethylene Guanidine Phosphate Depending on the Routes of Exposure
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DOI: 10.3390/ijms23063289
Abstract: Polyhexamethylene guanidine phosphate (PHMG-P), a cationic biocide, is widely used in household products due to its strong bactericidal activity and low toxicity. However, it causes fatal lung damage when inhaled. In this study, we investigated… read more here.
Keywords: disruption membrane; polyhexamethylene guanidine; guanidine phosphate; phmg ... See more keywords
Antibacterial Films Based on PVA and PVA–Chitosan Modified with Poly(Hexamethylene Guanidine)
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DOI: 10.3390/polym11122093
Abstract: In this study, thin, polymeric films consisting of poly(vinyl alcohol) (PVA) and chitosan (Ch) with the addition of poly(hexamethylene guanidine) (PHMG) were successfully prepared. The obtained materials were analyzed to determine their physicochemical and biocidal… read more here.
Keywords: pva chitosan; poly hexamethylene; phmg; spectroscopy ... See more keywords
Environmentally Friendly and Broad–Spectrum Antibacterial Poly(hexamethylene guanidine)–Modified Polypropylene and Its Antifouling Application
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DOI: 10.3390/polym15061521
Abstract: Biological fouling is one of the main reasons that limits the application of traditional polypropylene (PP) fishing nets in aquaculture. Here, a new environmentally friendly and broad–spectrum antibacterial agent called cationic poly(hexamethylene guanidine) (PHMG) was… read more here.
Keywords: phmg; friendly broad; environmentally friendly; spectrum antibacterial ... See more keywords