In vivo estrogenicity of p-phenoxyphenol and p-pentyloxyphenol
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-73271-1
Abstract: p-Alkoxyphenols (AOPs) are a class of ethers that are widely used in industrial and agricultural productions and daily necessities. p-Phenoxyphenol (PhOP) and p-pentyloxyphenol (PeOP) belong to this class and have been reported to be estrogenic… read more here.
Keywords: phop; phop peop; pentyloxyphenol; estrogenicity phenoxyphenol ... See more keywords
Convergence of two global regulators to coordinate expression of essential virulence determinants of Mycobacterium tuberculosis
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.1101/2022.06.30.498252
Abstract: Cyclic AMP (cAMP) is known to function as a global regulator of M. tuberculosis gene expression. Sequence-based transcriptomic profiling identified the mycobacterial regulon controlled by the cAMP receptor protein, CRP. In this study, we identified… read more here.
Keywords: tuberculosis; crp; expression; virulence determinants ... See more keywords
The regulation of antimicrobial peptide resistance in the transition to insect symbiosis
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Microbiology"
DOI: 10.1111/mmi.13598
Abstract: Many bacteria utilize two‐component systems consisting of a sensor kinase and a transcriptional response regulator to detect environmental signals and modulate gene expression for adaptation. The response regulator PhoP and its cognate sensor kinase PhoQ… read more here.
Keywords: phop; peptide; peptide resistance; antimicrobial peptide ... See more keywords
Activation of master virulence regulator PhoP in acidic pH requires the Salmonella-specific protein UgtL
Sign Up to like & getrecommendations! Published in 2017 at "Science Signaling"
DOI: 10.1126/scisignal.aan6284
Abstract: The Salmonella-specific protein UgtL augments acid-induced activation of a virulence regulator. A helping hand for acid sensing Activation of the PhoP/PhoQ two-component system of Salmonella enterica promotes the expression of virulence factors. Stimuli, such as… read more here.
Keywords: phop; salmonella; virulence; salmonella specific ... See more keywords
Acetylation of PhoP K88 Is Involved in Regulating Salmonella Virulence
Sign Up to like & getrecommendations! Published in 2020 at "Infection and Immunity"
DOI: 10.1128/iai.00588-20
Abstract: The PhoP-PhoQ two-component regulation system of Salmonella enterica serovar Typhimurium is involved in the response to various environmental stresses and is essential for bacterial virulence. Our previous studies showed that acetylation plays an important role… read more here.
Keywords: typhimurium; phop; salmonella; acetylation phop ... See more keywords
Serratia marcescens RamA Expression Is under PhoP-Dependent Control and Modulates Lipid A-Related Gene Transcription and Antibiotic Resistance Phenotypes
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Bacteriology"
DOI: 10.1128/jb.00523-20
Abstract: We demonstrate that in S. marcescens, the transcriptional regulator RamA is autoregulated and also controlled by the PhoP/PhoQ signal transduction system. We have shown that PhoP is able to directly and specifically bind to ramA,… read more here.
Keywords: lpxo2; rama; phop phoq; marcescens rama ... See more keywords
Methylation of PhoP by CheR Regulates Salmonella Virulence
Sign Up to like & getrecommendations! Published in 2021 at "mBio"
DOI: 10.1128/mbio.02099-21
Abstract: Posttranslational modifications (PTMs) play an important role in regulating enzyme activities, protein-protein interactions, or DNA-protein recognition and, consequently, modulate many biological functions. We demonstrated that PhoP, the response regulator of PhoP/PhoQ two-component system, could be… read more here.
Keywords: cher; salmonella virulence; phop; methylation phop ... See more keywords
Genome-Wide Analysis Reveals that PhoP Regulates Pathogenicity in Riemerella anatipestifer
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.01883-22
Abstract: Riemerella anatipestifer is a significant pathogen with high mortality in the poultry industry that causes acute septicemia and infectious polyserositis in ducks, chickens, geese, and other avian species. Previously, we characterized the two-component system encoded… read more here.
Keywords: phopr; pathogenicity; riemerella anatipestifer; analysis ... See more keywords
Phosphate regulator PhoP directly and indirectly controls transcription of the erythromycin biosynthesis genes in Saccharopolyspora erythraea
Sign Up to like & getrecommendations! Published in 2019 at "Microbial Cell Factories"
DOI: 10.1186/s12934-019-1258-y
Abstract: BackgroundThe choice of phosphate/nitrogen source and their concentrations have been shown to have great influences on antibiotic production. However, the underlying mechanisms responsible for this remain poorly understood.ResultsWe show that nutrient-sensing regulator PhoP (phosphate regulator)… read more here.
Keywords: transcription; phop; regulator; phosphate ... See more keywords
The PhoPQ Two-Component System Is the Major Regulator of Cell Surface Properties, Stress Responses and Plant-Derived Substrate Utilisation During Development of Pectobacterium versatile-Host Plant Pathosystems
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2020.621391
Abstract: Pectobacterium versatile (formerly P. carotovorum) is a recently defined species of soft rot enterobacteria capable of infecting many plant hosts and damaging different tissues. Complex transcriptional regulation of virulence properties can be expected for such… read more here.
Keywords: phop; plant; pectobacterium versatile; phopq two ... See more keywords
Arginine GlcNAcylation and Activity Regulation of PhoP by a Type III Secretion System Effector in Salmonella
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2021.825743
Abstract: Salmonella type III secretion system (T3SS) effector SseK3 is a glycosyltransferase delivered directly into the host cells to modify host protein substrates, thus manipulating host cellular signal transduction. Here, we identify and characterize the Arg-GlcNAcylation… read more here.
Keywords: phop; system; type iii; iii secretion ... See more keywords