Biphasic alcoholysis coupled with high speed countercurrent chromatography for high performance on separating phorbol from Croton tiglium Linn extracts.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of separation science"
DOI: 10.1002/jssc.202200984
Abstract: Phorbol is a tetracyclic diterpenoid found in Euphorbia tirucalli, Croton tiglium, and Rehmannia glutinosa, and is a nuclear of various phorbol esters. The rapid obtaining of phorbol with high purity highly contributes to its application, such as synthesizing… read more here.
Keywords: high speed; countercurrent chromatography; alcoholysis; biphasic alcoholysis ... See more keywords
Method validation for analysis of phorbol esters from Jatropha curcas
Sign Up to like & getrecommendations! Published in 2019 at "Industrial Crops and Products"
DOI: 10.1016/j.indcrop.2019.111627
Abstract: Abstract Jatropha curcas is a promising non-food source of oil for biodiesel. However, the presence of phorbol esters (PE) is the main limiting factor for utilization of defatted cakes for animal feed. Reliable methods of… read more here.
Keywords: jatropha curcas; method; extraction; phorbol esters ... See more keywords
Phorbol Esters from the Latex of Euphorbia umbellata: Bioguided Isolation of Highly Potent HIV-1 Latency Interrupters in Virus Reservoir Cells.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.0c01092
Abstract: Three known compounds, 20-deoxyphorbol-5β-hydroxy-12-tiglate-13-isobutyrate (1), 20-deoxyphorbol-5β-hydroxy-12-tiglate-13-phenylacetate (2), and 4-deoxy-4β-phorbol-12-tiglate-13-phenylacetate (3), were reisolated from the latex of Euphorbia umbellata through a bioguided fractionation process to target HIV-1 latency reactivation. The in vitro bioassay using infected T-cell… read more here.
Keywords: latency; euphorbia umbellata; hiv; latex euphorbia ... See more keywords
PSVI-4 Modulation of galectin gene expression and secretion in cow blood stimulated with Phorbol 12-myristate 13-acetate
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DOI: 10.1093/jas/skz258.403
Abstract: The objective of this study was to assess the expression and secretion of galectin gene in cow blood stimulated with Phorbol 12-myristate 13-acetate (PMA). Phorbol 12-myristate 13-acetate is a phorbol diester that activates the enzyme… read more here.
Keywords: secretion; galectin gene; cow blood; phorbol ... See more keywords
The Trace Element Selenium Is Important for Redox Signaling in Phorbol Ester-Differentiated THP-1 Macrophages
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms222011060
Abstract: Physiological selenium (Se) levels counteract excessive inflammation, with selenoproteins shaping the immunoregulatory cytokine and lipid mediator profile. How exactly differentiation of monocytes into macrophages influences the expression of the selenoproteome in concert with the Se… read more here.
Keywords: lipid mediator; phorbol; expression; differentiation ... See more keywords