Umpolung Phosphorylation of Tyrosine via 1,2-Phospha-Brook Rearrangement.
Sign Up to like & getrecommendations! Published in 2024 at "Organic letters"
DOI: 10.1021/acs.orglett.4c03223
Abstract: Phosphorylated tyrosine is a fundamental building block of bioactive peptides and proteins. However, the chemoselective phosphorylation of tyrosine over other nucleophilic amino acid residues in unprotected peptides remains a significant challenge. Here we report an… read more here.
Keywords: brook rearrangement; phospha brook; phosphorylation tyrosine; tyrosine ... See more keywords