Protein phosphatase 2A (PP2A) inhibition in NAFLD leads to an underlying intestinal fibrotic pathology that is NOX2 dependent
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.10.293
Abstract: Increased oxidative stress exacerbates the condition of Non-Alcoholic Fatty Liver Disease (NAFLD) which is a global pandemic, leading to its progression to the state of chronic inflammation and fibrosis (NASH). Protein phosphatase 2A (PP2A) is… read more here.
Keywords: phosphatase pp2a; protein phosphatase; pathology;
Co-expression network analysis of protein phosphatase 2A (PP2A) genes with stress-responsive genes in Arabidopsis thaliana reveals 13 key regulators
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-77746-z
Abstract: Abiotic and biotic stresses adversely affect plant growth and development and eventually result in less yield and threaten food security worldwide. In plants, several studies have been carried out to understand molecular responses to abiotic… read more here.
Keywords: stress responsive; phosphatase pp2a; analysis; pp2a genes ... See more keywords
The Protein Phosphatase PP2A-B′γ Takes Control over Salicylic Acid to Suppress Defense and Premature Senescence
Sign Up to like & getrecommendations! Published in 2020 at "Plant Physiology"
DOI: 10.1104/pp.19.01466
Abstract: Long thought to be unselective and often referred to as housekeeping enzymes, type 2A protein phosphatases (PP2As) have emerging specific regulatory functions in cell signaling ([Luan, 2003][1]; [Durian et al., 2016][2]; [Mathe et al., 2019][3]).… read more here.
Keywords: protein; pp2a takes; phosphatase pp2a; takes control ... See more keywords
Binding and Kinetic Analysis of Human Protein Phosphatase PP2A Interactions with Caspase 9 Protein and the Interfering Peptide C9h
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14102055
Abstract: The serine/threonine phosphatase PP2A and the cysteine protease Caspase 9 are two proteins involved in physiological and pathological processes, including cancer and apoptosis. We previously demonstrated the interaction between Caspase 9 and PP2A and identified… read more here.
Keywords: phosphatase pp2a; interfering peptide; pp2a; protein interfering ... See more keywords