Target-Based Discovery of an Inhibitor of the Regulatory Phosphatase PPP1R15B
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DOI: 10.1016/j.cell.2018.06.030
Abstract: Summary Protein phosphorylation is a prevalent and ubiquitous mechanism of regulation. Kinases are popular drug targets, but identifying selective phosphatase inhibitors has been challenging. Here, we used surface plasmon resonance to design a method to… read more here.
Keywords: target based; phosphatase; based discovery; target ... See more keywords