Strategies for Targeting Serine/Threonine Protein Phosphatases with Small Molecules in Cancer.
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DOI: 10.1021/acs.jmedchem.1c00631
Abstract: Among numerous posttranslational regulation patterns, phosphorylation is reversibly controlled by the balance of kinases and phosphatases. The major form of cellular signaling involves the reversible phosphorylation of proteins on tyrosine, serine, or threonine residues. However,… read more here.
Keywords: serine threonine; small molecules; targeting serine; phosphatases small ... See more keywords