Necessity of examining the practical efficacy of phosphate binders
Sign Up to like & getrecommendations! Published in 2021 at "Clinical and Experimental Nephrology"
DOI: 10.1007/s10157-021-02155-z
Abstract: Patients on maintenance hemodialysis (HD) generally require management of hyperphosphatemia and take phosphate binders (PBs) such as ferric citrate (FC) and lanthanum carbonate (LC) [1]. Meanwhile, many HD patients require antacid therapy (AAT). Although PBs… read more here.
Keywords: lc250; phosphate binders; aat; efficacy ... See more keywords
The hollow core-shell ferric oxide entrapped chitosan microcapsules as phosphate binders for phosphorus removal in vitro.
Sign Up to like & getrecommendations! Published in 2021 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2021.117621
Abstract: Patients in hyperphosphatemia are orally prescribed with phosphate binders to excrete the non-metabolic phosphorus. Aiming for the bio-compatibility and binding efficacy, the Fe-based phosphate binders of low toxicity have been explored and improved. Herein, the… read more here.
Keywords: core shell; ferric oxide; hollow core; phosphate binders ... See more keywords
Gut microbiota; an overlooked effect of phosphate binders.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2019.172892
Abstract: Hyperphosphatemia is a mineral bone-disease that increases cardiovascular complications and all-cause mortality in chronic kidney disease (CKD) patients. Oral phosphate binders absorb the dietary phosphate to prevent its high plasma levels. Moreover, they can adsorb… read more here.
Keywords: phosphate binders; binders gut; gut microbiota; phosphate ... See more keywords
An update on phosphate binders for the treatment of hyperphosphatemia in chronic kidney disease patients on dialysis: a review of safety profiles
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Drug Safety"
DOI: 10.1080/14740338.2022.2044472
Abstract: ABSTRACT Introduction Hyperphosphatemia is an inevitable complication for patients undergoing dialysis, as is the resulting need for treatment with phosphate binders. Currently, various phosphate binders are clinically available. In addition to their phosphate-lowering activity, individual… read more here.
Keywords: phosphate; hyperphosphatemia; safety profiles; treatment ... See more keywords
MO797JUXTAPOSING THE EFFICACIES BETWEEN IRON-BASED AND NON-CALCIUM PHOSPHATE BINDERS FOR IMPROVING MINERAL AND BONE DISORDER PARAMETERS IN DIALYSIS-DEPENDENT CHRONIC KIDNEY DISEASE PATIENTS: A META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS
Sign Up to like & getrecommendations! Published in 2021 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfab096.006
Abstract: Hyperphosphatemia is a serious complication in chronic kidney disease (CKD) patients that serves as the main risk factor of CKD–mineral and bone disorder (CKD-MBD) progression. Previous studies suggested that iron-based phosphate binder showed better improvement… read more here.
Keywords: phosphate; smd; iron based; non calcium ... See more keywords
Non calcium phosphate binders - Is there any evidence of benefit
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Nephrology and Hypertension"
DOI: 10.1097/mnh.0000000000000796
Abstract: Purpose of review Low-level evidence and opinion-based clinical practice guidelines highlight the substantial uncertainty in the practice patterns of hyperphosphatemia management in patients with chronic kidney disease (CKD). This manuscript reviews the evidence for the… read more here.
Keywords: phosphate; non calcium; based binders; evidence ... See more keywords
Effects of phosphate binders on bone biomarkers and bone density in haemodialysis patients
Sign Up to like & getrecommendations! Published in 2022 at "Nephrology"
DOI: 10.1111/nep.14022
Abstract: The incidences of osteoporosis, fracture and vascular calcification increase concordantly with the progression of chronic kidney disease (CKD). CKD‐mineral bone disease (CKD‐MBD) induced by hyperphosphatemia is a major pathophysiologic mechanism. The effects of phosphate binders… read more here.
Keywords: effects phosphate; binders bone; haemodialysis patients; density ... See more keywords
Phosphate Binders and Targets Over Decades: Do We have it Right Now?
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DOI: 10.1111/sdi.12568
Abstract: In advanced renal disease, the kidney is unable to maintain phosphate balance due to decreased urinary excretion as well as the imbalance of the bone metabolic axis. It is well established that hyperphosphatemia is associated… read more here.
Keywords: phosphate binders; binders targets; targets decades; disease ... See more keywords