On the Origins of Enzymes: Phosphate-Binding Polypeptides Mediate Phosphoryl Transfer to Synthesize Adenosine Triphosphate
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DOI: 10.1021/jacs.2c08636
Abstract: Reactions involving the transfer of a phosphoryl (−PO32–) group are fundamental to cellular metabolism. These reactions are catalyzed by enzymes, often large and complex, belonging to the phosphate-binding loop (P-loop) nucleoside triphosphatase (NTPase) superfamily. Due… read more here.
Keywords: phosphate binding; transfer; synthesize adenosine; phosphoryl transfer ... See more keywords
Biochemical and structural characterization of the cyanophage-encoded phosphate binding protein: implications for enhanced phosphate uptake of infected cyanobacteria.
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DOI: 10.1111/1462-2920.16043
Abstract: To acquire phosphorus, cyanobacteria use the typical bacterial ABC-type phosphate transporter, which is composed of a periplasmic high-affinity phosphate-binding protein PstS and a channel formed by two transmembrane proteins PstC and PstA. A putative pstS… read more here.
Keywords: phosphate binding; binding protein; cyanophage; biochemical structural ... See more keywords
Comparative Efficacy and Safety of Phosphate Binders in Hyperphosphatemia Patients With Chronic Kidney Disease
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DOI: 10.1177/0148607117715440
Abstract: BACKGROUND In this study, we coordinated a network meta-analysis to establish the efficacy and safety of different agents used in the treatment of hyperphosphatemia patients with chronic kidney disease. METHODS PubMed, CNKI, and Embase were… read more here.
Keywords: efficacy safety; phosphate binding; based phosphate; phosphate ... See more keywords
The Conserved Family of the Pyridoxal Phosphate-Binding Protein (PLPBP) and Its Cyanobacterial Paradigm PipY
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DOI: 10.3390/life12101622
Abstract: The PLPBP family of pyridoxal phosphate-binding proteins has a high degree of sequence conservation and is represented in all three domains of life. PLPBP members, of which a few representatives have been studied in different… read more here.
Keywords: phosphate binding; family; pyridoxal phosphate; plp ... See more keywords