Effects of empagliflozin on markers of calcium and phosphate homeostasis in patients with type 2 diabetes – Data from a randomized, placebo-controlled study
Sign Up to like & getrecommendations! Published in 2022 at "Bone Reports"
DOI: 10.1016/j.bonr.2022.101175
Abstract: Background and aim Sodium-glucose cotransporter-2 (SGLT2) inhibitors, glucose-lowering drugs that increase urinary glucose excretion have been shown to reduce CV events in patients with type 2 diabetes (T2D). Furthermore, several studies have demonstrated that treatment… read more here.
Keywords: phosphate homeostasis; calcium phosphate; placebo; treatment ... See more keywords
Mechanical loading modulates phosphate related genes in rat bone
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DOI: 10.1371/journal.pone.0282678
Abstract: Mechanical loading determines bone mass and bone structure, which involves many biochemical signal molecules. Of these molecules, Mepe and Fgf23 are involved in bone mineralization and phosphate homeostasis. Thus, we aimed to explore whether mechanical… read more here.
Keywords: phosphate homeostasis; mechanical loading; fgf23; bone ... See more keywords
Phosphate Homeostasis and Disorders of Phosphate metabolism.
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DOI: 10.2174/1573396319666221221121350
Abstract: Phosphate is indispensable for human life and evolutionary changes over several millions of years have established tightly regulated mechanisms to ensure phosphate homeostasis. In this process, calcium and phosphate metabolism have come to be intricately… read more here.
Keywords: phosphate; phosphate metabolism; calcium phosphate; phosphate homeostasis ... See more keywords
The Complexities of Organ Crosstalk in Phosphate Homeostasis: Time to Put Phosphate Sensing Back in the Limelight
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DOI: 10.3390/ijms22115701
Abstract: Phosphate homeostasis is essential for health and is achieved via interaction between the bone, kidney, small intestine, and parathyroid glands and via intricate processes involving phosphate transporters, phosphate sensors, and circulating hormones. Numerous genetic and… read more here.
Keywords: complexities organ; phosphate homeostasis; phosphate sensors; phosphate sensing ... See more keywords
A tRNA modification balances carbon and nitrogen metabolism by regulating phosphate homeostasis
Sign Up to like & getrecommendations! Published in 2019 at "eLife"
DOI: 10.7554/elife.44795
Abstract: Cells must appropriately sense and integrate multiple metabolic resources to commit to proliferation. Here, we report that S. cerevisiae cells regulate carbon and nitrogen metabolic homeostasis through tRNA U34-thiolation. Despite amino acid sufficiency, tRNA-thiolation deficient… read more here.
Keywords: homeostasis; trna; homeostasis trna; carbon nitrogen ... See more keywords