LYSET/TMEM251/GCAF is critical for autophagy and lysosomal function by regulating the mannose-6-phosphate (M6P) pathway
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DOI: 10.1080/15548627.2023.2167375
Abstract: ABSTRACT Vertebrate cells rely on mannose-6-phosphate (M6P) modifications to deliver most lumenal hydrolases to the lysosome. As a critical trafficking signal for lysosomal enzymes, the M6P biosynthetic pathway has been thoroughly investigated. However, its regulatory… read more here.
Keywords: phosphate m6p; pathway; lyset tmem251; mannose phosphate ... See more keywords