Phosphate Toxicity and Epithelial to Mesenchymal Transition.
Sign Up to like & getrecommendations! Published in 2022 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-91623-7_8
Abstract: The underlying role of inadequate or excess intake of phosphate is evident in disease states, including metabolic, skeletal, cardiac, kidney and various cancers. Elevated phosphate levels can induce epithelial to mesenchymal transition (EMT) and cell… read more here.
Keywords: mesenchymal transition; epithelial mesenchymal; phosphate toxicity; phosphate ... See more keywords
Can targeting the FGF23-αKlotho signaling system delay phosphate-driven organ damage?
Sign Up to like & getrecommendations! Published in 2025 at "Expert Opinion on Therapeutic Targets"
DOI: 10.1080/14728222.2025.2482552
Abstract: ABSTRACT Introduction Inexorable high serum phosphate levels in chronic kidney disease (CKD) patients deteriorate the functionality of the musculoskeletal, renal, and cardiovascular systems, thereby contributing to increased morbidity and mortality. Higher phosphate balance has also… read more here.
Keywords: organ damage; signaling system; phosphate toxicity; phosphate ... See more keywords
Modifying Phosphate Toxicity in Chronic Kidney Disease
Sign Up to like & getrecommendations! Published in 2019 at "Toxins"
DOI: 10.3390/toxins11090522
Abstract: Phosphate toxicity is a well-established phenomenon, especially in chronic kidney disease (CKD), where hyperphosphatemia is a frequent occurrence when CKD is advanced. Many therapeutic efforts are targeted at phosphate, and comprise dietary intervention, modifying dialysis… read more here.
Keywords: phosphate toxicity; kidney disease; disease; chronic kidney ... See more keywords