Phosphates Drive the Assembly of Fibers Made from the α-Helical Lentiviral Transduction Enhancer Vectofusin.
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DOI: 10.1021/acs.biomac.5c00554
Abstract: Vectofusin (VF) is a histidine-rich amphipathic peptide designed to enhance lentiviral transduction for gene therapeutic applications, where its assembly into fibrils requires polyvalent anions. In this study, we used solid-state NMR, transmission electron microscopy, and… read more here.
Keywords: lentiviral transduction; drive assembly; phosphates drive; vectofusin ... See more keywords