Testing Pollen Tube Proteins for In Vivo Binding to Phosphatidic Acid by n-Butanol Treatment and Confocal Microscopy.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0672-8_22
Abstract: The general role of cellular membranes is to provide a barrier and to generate separate reaction spaces. However, additional functions of membrane domains enriched in certain classes of lipids have been discovered, which represent an… read more here.
Keywords: butanol; microscopy; phosphatidic acid; pollen ... See more keywords
2-Carba cyclic phosphatidic acid inhibits lipopolysaccharide-induced prostaglandin E2 production in a human macrophage cell line
Sign Up to like & getrecommendations! Published in 2019 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2019.100668
Abstract: Cyclic phosphatidic acid (cPA) is a naturally occurring phospholipid mediator that contains a unique cyclic phosphate ring at the sn-2 and sn-3 positions of its glycerol backbone. Using mouse models for multiple sclerosis (cuprizone-induced demyelination… read more here.
Keywords: cyclic phosphatidic; cell line; phosphatidic acid;
Mono- and Poly-unsaturated Phosphatidic Acid Regulate Distinct Steps of Regulated Exocytosis in Neuroendocrine Cells.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.108026
Abstract: Specific forms of fatty acids are well known to have beneficial health effects, but their precise mechanism of action remains elusive. Phosphatidic acid (PA) produced by phospholipase D1 (PLD1) regulates the sequential stages underlying secretory… read more here.
Keywords: exocytosis neuroendocrine; mono poly; poly unsaturated; phosphatidic acid ... See more keywords
The effect of acute oral phosphatidic acid ingestion on myofibrillar protein synthesis and intracellular signaling in older males.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical nutrition"
DOI: 10.1016/j.clnu.2018.06.963
Abstract: BACKGROUND Age-related muscle loss (sarcopenia) may be driven by a diminished myofibrillar protein synthesis (MyoPS) response to anabolic stimuli (i.e. exercise and nutrition). Oral phosphatidic acid (PA) ingestion has been reported to stimulate resting muscle… read more here.
Keywords: acid ingestion; protein synthesis; phosphatidic acid; ingestion ... See more keywords
Effects of micro wet milling on bioaccessibility of phosphatidic acid and lysophosphatidic acid in komatsuna during in vitro digestion.
Sign Up to like & getrecommendations! Published in 2019 at "Food research international"
DOI: 10.1016/j.foodres.2019.01.021
Abstract: Foods rich in phosphatidic acid (PA) can ameliorate stomach ulcers in mice by hydrolysis of PA to lysophosphatidic acid (LPA). In this study, PA-rich komatsuna was produced using the micro wet milling (MWM) system, which… read more here.
Keywords: komatsuna; digestion; micro wet; lysophosphatidic acid ... See more keywords
Structural basis of DEPTOR to recognize phosphatidic acid using its tandem DEP domains.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2021.166989
Abstract: DEP domain containing mTOR-interacting protein (DEPTOR) plays pivotal roles in regulating metabolism, growth, autophagy and apoptosis by functions as an endogenous inhibitor of mTOR signaling pathway. Activated by phosphatidic acid, a second messenger in mTOR… read more here.
Keywords: acid using; dep domains; tandem dep; phosphatidic acid ... See more keywords
The neuroprotective function of 2-carba-cyclic phosphatidic acid: Implications for tenascin-C via astrocytes in traumatic brain injury
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Neuroimmunology"
DOI: 10.1016/j.jneuroim.2021.577749
Abstract: We examined the mechanism how 2-carba-cyclic phosphatidic acid (2ccPA), a lipid mediator, regulates neuronal apoptosis in traumatic brain injury (TBI). First, we found 2ccPA suppressed neuronal apoptosis after the injury, and increased the immunoreactivity of… read more here.
Keywords: traumatic brain; carba cyclic; cyclic phosphatidic; phosphatidic acid ... See more keywords
Regulation of the Hippo Pathway by Phosphatidic Acid-Mediated Lipid-Protein Interaction.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular cell"
DOI: 10.1016/j.molcel.2018.08.038
Abstract: The Hippo pathway plays a crucial role in organ size control and tumor suppression, but its precise regulation is not fully understood. In this study, we discovered that phosphatidic acid (PA)-related lipid signaling is a… read more here.
Keywords: lipid signaling; regulation hippo; pathway phosphatidic; phosphatidic acid ... See more keywords
Brassinosteroids application induces phosphatidic acid production and modify antioxidant enzymes activity in tobacco in calcium-dependent manner
Sign Up to like & getrecommendations! Published in 2021 at "Steroids"
DOI: 10.1016/j.steroids.2019.108444
Abstract: Brassinosteroids (BRs) are steroid hormones regulating various aspects of plant metabolism, including growth, development and stress responses. However, little is known about the mechanism of their impact on antioxidant systems and phospholipid turnover. Using tobacco… read more here.
Keywords: tobacco; production; application induces; brassinosteroids application ... See more keywords
Molecular View into Preferential Binding of the Factor VII Gla Domain to Phosphatidic Acid.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemistry"
DOI: 10.1021/acs.biochem.2c00266
Abstract: Factor VII (FVII) is a serine protease with a key role in initiating the coagulation cascade. It is part of a family of vitamin K-dependent clotting proteins, which require vitamin K for formation of their… read more here.
Keywords: binding; gla domain; factor vii; phosphatidic acid ... See more keywords
Lipid Metabolomic and Transcriptomic Analyses Reveal That Phosphatidylcholine Enhanced the Resistance of Peach Seedlings to Salt Stress through Phosphatidic Acid.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.3c01383
Abstract: Soil salinity is a major conlinet limiting sustainable agricultural development in peach tree industry. In this study, lipid metabolomic pathway analysis indicated that phosphatidic acid is essential for root resistance to salt stress in peach… read more here.
Keywords: peach; lipid metabolomic; phosphatidic acid; resistance ... See more keywords