Phosphatidylethanolamine functionalized biomimetic monolith for immobilized artificial membrane chromatography
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Pharmaceutical Analysis"
DOI: 10.1016/j.jpha.2021.09.002
Abstract: Abstract In this research, a new phospholipid based monolith was fabricated by in situ co-polymerization of 1-dodecanoyl-2-(11-methacrylamidoundecanoyl)-sn-glycero-3-phosphoethanolamine (MDSPE) and ethylene dimethacrylate (EDMA) to mimic bio-membrane environment. Excellent physicochemical properties of this novel monolith were achieved,… read more here.
Keywords: immobilized artificial; artificial membrane; phosphatidylethanolamine; biomimetic monolith ... See more keywords
Sugar-based bactericides targeting phosphatidylethanolamine-enriched membranes
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-06488-4
Abstract: Anthrax is an infectious disease caused by Bacillus anthracis, a bioterrorism agent that develops resistance to clinically used antibiotics. Therefore, alternative mechanisms of action remain a challenge. Herein, we disclose deoxy glycosides responsible for specific… read more here.
Keywords: phosphatidylethanolamine; sugar based; targeting phosphatidylethanolamine; phosphatidylethanolamine enriched ... See more keywords
The DedA superfamily member PetA is required for the transbilayer distribution of phosphatidylethanolamine in bacterial membranes.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2301979120
Abstract: The sorting of phospholipids between the inner and outer leaflets of the membrane bilayer is a fundamental problem in all organisms. Despite years of investigation, most of the enzymes that catalyze phospholipid reorientation in bacteria… read more here.
Keywords: duramycin; superfamily member; deda superfamily; peta required ... See more keywords
Phosphatidylethanolamine and Phosphatidylserine Synergize To Enhance GAS6/AXL-Mediated Virus Infection and Efferocytosis
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DOI: 10.1128/jvi.02079-20
Abstract: Phosphatidylserine (PS) and phosphatidylethanolamine (PE) are usually sequestered to the inner leaflet of the plasma membrane of the healthy eukaryotic cells. During apoptosis, these phospholipids move to the cell’s outer leaflet where they are recognized… read more here.
Keywords: efferocytosis; entry; virus infection; phosphatidylethanolamine ... See more keywords
Loss of the Major Phosphatidylserine or Phosphatidylethanolamine Flippases Differentially Affect Phagocytosis
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.00648
Abstract: The lipids phosphatidylserine (PtdSer) and phosphatidylethanolamine (PtdEth) are normally asymmetrically localized to the cytosolic face of membrane bilayers, but can both be externalized during diverse biological processes, including cell division, cell fusion, and cell death.… read more here.
Keywords: cell; phagocytosis; phosphatidylethanolamine; ptdser ptdeth ... See more keywords
Phosphatidylethanolamine homeostasis under conditions of impaired CDP-ethanolamine pathway or phosphatidylserine decarboxylation
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2022.1094273
Abstract: Phosphatidylethanolamine is the major inner-membrane lipid in the plasma and mitochondrial membranes. It is synthesized in the endoplasmic reticulum from ethanolamine and diacylglycerol (DAG) by the CDP-ethanolamine pathway and from phosphatidylserine by decarboxylation in the… read more here.
Keywords: cdp ethanolamine; phosphatidylserine decarboxylation; phosphatidylethanolamine; ethanolamine pathway ... See more keywords