Enzymatic kinetic resolution of desmethylphosphinothricin indicates that phosphinic group is a bioisostere of carboxyl group
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DOI: 10.1038/s42004-020-00368-z
Abstract: Escherichia coli glutamate decarboxylase ( Ec GadB), a pyridoxal 5’-phosphate (PLP)-dependent enzyme, is highly specific for L -glutamate and was demonstrated to be effectively immobilised for the production of γ-aminobutyric acid (GABA), its decarboxylation product.… read more here.
Keywords: phosphinic group; group; bioisostere carboxyl; carboxyl group ... See more keywords