Increased Phospho‐AKT in Blood Cells from LRRK2 G2019S Mutation Carriers
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26469
Abstract: The purpose of this study was to investigate whether differential phosphorylation states of blood markers can identify patients with LRRK2 Parkinson's disease (PD). We assessed phospho(P)‐Ser‐935‐LRRK2 and P‐Ser‐473‐AKT levels in peripheral blood cells from patients… read more here.
Keywords: ser 473; blood cells; increased phospho; blood ... See more keywords
Correlation between immunohistochemistry and RICTOR FISH amplification in small cell lung carcinoma.
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DOI: 10.1016/j.humpath.2019.08.018
Abstract: Small cell lung carcinoma (SCLC) accounts for approximately 15% of all lung cancers and remains a challenging disease, with no significant improvement in the field of targeted therapies. The RICTOR gene (rapamycin-insensitive companion of mTOR… read more here.
Keywords: rictor; ihc; rictor fish; phospho akt ... See more keywords
Overexpression of COPS3 promotes clear cell renal cell carcinoma progression via regulation of Phospho–AKT(Thr308), Cyclin D1 and Caspase–3
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Cell Research"
DOI: 10.1016/j.yexcr.2018.02.025
Abstract: ABSTRACT The third subunit of the COP9 signalosome (COPS3) is associated with cell proliferation and tumorigenesis process in cancer. The present study showed that the expression level of COPS3 was upregulated in malignant cell lines… read more here.
Keywords: akt thr308; thr308 cyclin; cops3; phospho akt ... See more keywords