Global Proteome and Phospho-proteome Analysis of Merlin-deficient Meningioma and Schwannoma Identifies PDLIM2 as a Novel Therapeutic Target
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DOI: 10.1016/j.ebiom.2017.01.020
Abstract: Loss or mutation of the tumour suppressor Merlin predisposes individuals to develop multiple nervous system tumours, including schwannomas and meningiomas, sporadically or as part of the autosomal dominant inherited condition Neurofibromatosis 2 (NF2). These tumours… read more here.
Keywords: meningioma; phospho proteome; proteome phospho; meningioma schwannoma ... See more keywords
The cardiac phospho-proteome during pressure overload in mice
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DOI: 10.1038/s41597-025-05506-7
Abstract: Transaortic constriction (TAC) is a murine model of pressure overload-induced cardiac hypertrophy and heart failure. Despite its high prevalence during aortic stenosis or chronic arterial hypertension, the global alterations in cardiac phospho-proteome dynamics following TAC… read more here.
Keywords: phospho; phospho proteome; pressure overload; cardiac phospho ... See more keywords