Spatial-proteomics reveals phospho-signaling dynamics at subcellular resolution
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-27398-y
Abstract: Dynamic change in subcellular localization of signaling proteins is a general concept that eukaryotic cells evolved for eliciting a coordinated response to stimuli. Mass spectrometry-based proteomics in combination with subcellular fractionation can provide comprehensive maps… read more here.
Keywords: phospho signaling; spatial proteomics; reveals phospho; proteomics reveals ... See more keywords
Human phospho‐signaling networks of SARS‐CoV‐2 infection are rewired by population genetic variants
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Systems Biology"
DOI: 10.15252/msb.202110823
Abstract: SARS‐CoV‐2 infection hijacks signaling pathways and induces protein–protein interactions between human and viral proteins. Human genetic variation may impact SARS‐CoV‐2 infection and COVID‐19 pathology; however, the genetic variation in these signaling networks remains uncharacterized. Here,… read more here.
Keywords: phospho signaling; signaling networks; human phospho; cov infection ... See more keywords