Dipole Orientation Matters: Longer-Circulating Choline Phosphate than Phosphocholine Liposomes for Enhanced Tumor Targeting.
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DOI: 10.1021/acsami.7b03160
Abstract: Zwitterionic phosphocholine (PC) liposomes are widely used in drug delivery because of their high biocompatibility and long blood circulation time. We herein report that by flipping the direction of the PC dipole, the resulting choline… read more here.
Keywords: circulation time; phosphocholine liposomes; choline phosphate;