Design and synthesis of novel annulated thienopyrimidines as phosphodiesterase 5 (PDE5) inhibitors
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DOI: 10.1002/ardp.201800018
Abstract: Novel cycloalkene‐fused thienopyrimidine analogues with enhanced phosphodiesterase 5 (PDE5) inhibitory properties are presented. The structure of the reported scaffold was modulated through variation of the terminal cycloalkene ring size, as well as by varying the… read more here.
Keywords: design synthesis; synthesis novel; phosphodiesterase; phosphodiesterase pde5 ... See more keywords