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Published in 2019 at "Drug Development and Industrial Pharmacy"
DOI: 10.1080/03639045.2019.1583755
Abstract: Abstract Objective: To prepare and characterize an optimized phospholipid complex of Ursolic acid (UA) to overcome the poor pharmacokinetic properties and to investigate the impact of the complex on hepatoprotective activity and bioavailability in animal…
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Keywords:
methodology;
phospholipid complex;
ursolic acid;
bioavailability ... See more keywords
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Published in 2017 at "Drug Delivery"
DOI: 10.1080/10717544.2017.1311968
Abstract: Abstract Phospholipid complex is one of the most successful approaches for enhancing oral bioavailability of poorly absorbed plant constituents. But the sticky property of phospholipids results in an unsatisfactory dissolution of drugs. In this study,…
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Keywords:
oral bioavailability;
bapc;
phospholipid complex;
baicalein ... See more keywords
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Published in 2020 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2020.1835956
Abstract: Abstract Piper species is one of the most widely consumed spices for culinary purposes. Piperine (PIP) present in Piper species has a wide range of therapeutic activity including hepatoprotection. However, the major biological limitation of…
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Keywords:
phospholipid complex;
bioavailability;
ppc;
pip ... See more keywords
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Published in 2023 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2023.2165102
Abstract: Abstract The present study aimed to improve the neuroprotective effect of chrysin (CHR) by combining two formulation techniques, phospholipid (PL) complexation and solid dispersion (SD). CHR-phospholipid complex (CHR-PLC) was prepared through solvent evaporation. The molar…
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Keywords:
solid dispersion;
plain chr;
chr plc;
phospholipid complex ... See more keywords
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Published in 2018 at "Poultry Science"
DOI: 10.3382/ps/pey155
Abstract: Abstract Duck hepatitis A virus type 1 (DHAV‐1) is one of the main pathogens of ducklings and causes a high mortality rate. Baicalin (BA) has potent antiviral effect, but the solubility is very poor. In…
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Keywords:
dhav;
phospholipid complex;
antiviral effect;
virus type ... See more keywords