STAT3 Cooperates With Phospholipid Scramblase 2 to Suppress Type I Interferon Response
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.01886
Abstract: Type I interferon (IFN-I) is a pluripotent cytokine that modulates innate and adaptive immunity. We have previously shown that STAT3 suppresses IFN-I response in a manner dependent on its N-terminal domain (NTD), but independent of… read more here.
Keywords: type interferon; response; stat3; plscr2 ... See more keywords
Phospholipid Scramblase 4 (PLSCR4) Regulates Adipocyte Differentiation via PIP3-Mediated AKT Activation
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DOI: 10.3390/ijms23179787
Abstract: Phospholipid scramblase 4 (PLSCR4) is a member of a conserved enzyme family with high relevance for the remodeling of phospholipid distribution in the plasma membrane and the regulation of cellular signaling. While PLSCR1 and -3… read more here.
Keywords: pip3; phospholipid scramblase; adipose tissue; scramblase plscr4 ... See more keywords
TMEM41B, a novel ER phospholipid scramblase mediating systemic lipid metabolism
Sign Up to like & getrecommendations! Published in 2022 at "Acta Biochimica et Biophysica Sinica"
DOI: 10.3724/abbs.2022168
Abstract: The phospholipid molecules forming the phospholipid bilayer membrane have difficulties to complete spontaneous trans-bilayer shuttling due to the physicochemical properties and biological functions of the membrane bilayer [1]. However, this transbilayer phospholipid transport is essential… read more here.
Keywords: phospholipid scramblase; novel phospholipid; systemic lipid; mediating systemic ... See more keywords