Hydroxyphenylamine phosphonate derivatives: Synthesis, X-ray crystallographic analysis, and evaluation of theirs anti-Alzheimer effects and antioxidant activities
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2020.129121
Abstract: Abstract The present study deals with the synthesis and characterization by single-crystal X-ray analysis, UV-Vis and FT-IR spectroscopy of two new α-aminophosphonates molecules: ((2-Hydroxy-5-methyl-phenylamino)-phenyl-methyl)-phosphonic acid diethyl ester (MAPH) and ((2-Hydroxy-5-nitro-phenylamino)-phenyl-methyl)-phosphonic acid diethyl ester (NAPH), based… read more here.
Keywords: analysis; phosphonate derivatives; maph; two molecules ... See more keywords
Synthesis of phosphonate derivatives of 2′-deoxy-2′-fluorotetradialdose d-nucleosides and tetradialdose d-nucleosides
Sign Up to like & getrecommendations! Published in 2021 at "Tetrahedron"
DOI: 10.1016/j.tet.2021.132159
Abstract: Analogs of nucleosides and nucleotides represent a promising pool of potential therapeutics. This work describes a new synthetic route leading to 2'-deoxy-2'-fluorotetradialdose D-nucleoside phosphonates. Moreover, a new universal synthetic route leading to tetradialdose d-nucleosides bearing… read more here.
Keywords: tetradialdose nucleosides; deoxy fluorotetradialdose; derivatives deoxy; phosphonate derivatives ... See more keywords
Analysis and application of the SRBSDV P9-1 octamer crystal structure for the target of α-amino phosphonate derivatives
Sign Up to like & getrecommendations! Published in 2018 at "Oncotarget"
DOI: 10.18632/oncotarget.24243
Abstract: Southern rice black-streaked dwarf virus (SRBSDV) P9-1 octameric protein accumulates viroplasms in SRBSDV-infected plant and insect cells, our previous studies found α-amino phosphonate drug—dufulin had a micromole affinity with SRBSDV P9-1. Now we focus our… read more here.
Keywords: crystal structure; srbsdv; phosphonate derivatives; target amino ... See more keywords