Facile synthesis of Fmoc-protected phosphonate pSer mimetic and its application in assembling a substrate peptide of 14-3-3 ΞΆ
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DOI: 10.1016/j.tetlet.2017.05.037
Abstract: Abstract Phosphatase-inert peptidomimetics containing phosphonate pSer analogue have been developed as valuable biological tools for probing and regulating pSer-dependent protein-protein interactions (PPIs) in cellular context. Herein, we report a facile and efficient synthesis route of… read more here.
Keywords: peptide; phosphonate pser; fmoc protected; synthesis ... See more keywords