Phosphonoacetate Modifications Enhance the Stability and Editing Yields of Guide RNAs for Cas9 Editors.
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DOI: 10.1021/acs.biochem.1c00768
Abstract: CRISPR gene editing and control systems continue to emerge and inspire novel research and clinical applications. Advances in CRISPR performance such as optimizing the duration of activity in cells, tissues, and organisms, as well as… read more here.
Keywords: modified ends; modifications enhance; guide rnas; editing yields ... See more keywords