Quest for the Crypto‐phosphoproteome
Sign Up to like & getrecommendations! Published in 2020 at "ChemBioChem"
DOI: 10.1002/cbic.202000583
Abstract: Protein phosphorylation is one of the most studied post‐translational modifications (PTMs). Despite the remarkable advances in phosphoproteomics, a chemically less‐stable subset of the phosphosites, which we call the crypto‐phosphoproteome, has remained underexplored due to technological… read more here.
Keywords: crypto phosphoproteome; quest crypto; phosphoproteome;
Phosphoproteome Profiling Using an Isobaric Carrier without the Need for Phosphoenrichment.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c04188
Abstract: Phosphorylation is a crucial component of cellular signaling cascades. It controls a variety of biological cellular functions, including cell growth and apoptosis. Owing to the low stoichiometry of phosphorylated proteins, the enrichment of phosphopeptides prior… read more here.
Keywords: carrier; isobaric carrier; phosphoproteome profiling; profiling using ... See more keywords
Deep Phosphoproteome Landscape of Interhemispheric Functionality of Neuroanatomical Regions of the Human Brain.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.2c00244
Abstract: Post-translational modifications (PTMs) are one of the compulsive and predominant biological processes that regulate the diverse molecular mechanism, modulate the onset of disease, and are the reason behind the functional diversity of proteins. Despite the… read more here.
Keywords: brain; neuroanatomical regions; phosphoproteome; human brain ... See more keywords
Phage-Displayed SH2 Domain Libraries: From Ultrasensitive Tyrosine Phosphoproteome Probes to Translational Research.
Sign Up to like & getrecommendations! Published in 2023 at "Cold Spring Harbor protocols"
DOI: 10.1101/pdb.over107981
Abstract: Tyrosine phosphorylation is a critical regulator of cell signaling. A large fraction of the tyrosine phosphoproteome, however, remains uncharacterized, largely due to a lack of robust and scalable methods. The Src homology 2 (SH2) domain,… read more here.
Keywords: tyrosine phosphoproteome; sh2 domains; sh2 domain; phosphoproteome ... See more keywords