Reconstructing phosphorylation signalling networks from quantitative phosphoproteomic data
Sign Up to like & getrecommendations! Published in 2018 at "Essays in Biochemistry"
DOI: 10.1042/ebc20180019
Abstract: Cascades of phosphorylation between protein kinases comprise a core mechanism in the integration and propagation of intracellular signals. Although we have accumulated a wealth of knowledge around some such pathways, this is subject to study… read more here.
Keywords: reconstructing phosphorylation; quantitative phosphoproteomic; signalling networks; phosphoproteomic data ... See more keywords
Bioinformatics Analysis of Global Proteomic and Phosphoproteomic Data Sets Revealed Activation of NEK2 and AURKA in Cancers
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DOI: 10.3390/biom10020237
Abstract: Tumor heterogeneity attributes substantial challenges in determining the treatment regimen. Along with the conventional treatment, such as chemotherapy and radiotherapy, targeted therapy has greater impact in cancer management. Owing to the recent advancements in proteomics,… read more here.
Keywords: data sets; analysis; proteomic phosphoproteomic; aurka ... See more keywords