Influence of Renal Function on Phosphoramide Mustard Exposure: A Nonlinear MixedâEffects Analysis
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DOI: 10.1002/jcph.2144
Abstract: Phosphoramide mustard (PM) is the final cytotoxic metabolite formed from the parent compound cyclophosphamide through a complex metabolic pathway, primarily through hepatic metabolism. Little is known about the effect of renal elimination on the disposition… read more here.
Keywords: mixed effects; function; phosphoramide mustard; renal function ... See more keywords