A Trisbenzimidazole Phosphoramidite Building Block Enables High-Yielding Syntheses of RNA-Cleaving Oligonucleotide Conjugates
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DOI: 10.3390/molecules25081842
Abstract: The RNA cleaving catalyst tris(2-aminobenzimidazole) when attached to the 5’ terminus of oligonucleotides cuts complementary RNA strands in a highly site-specific manner. Conjugation was previously achieved by the acylation of an amino linker by an… read more here.
Keywords: trisbenzimidazole phosphoramidite; building block; phosphoramidite building; building ... See more keywords