Distinct domains of Escherichia coli IgaA connect envelope stress sensing and down-regulation of the Rcs phosphorelay across subcellular compartments
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DOI: 10.1371/journal.pgen.1007398
Abstract: In enterobacteria, the Rcs system (Regulator of capsule synthesis) monitors envelope integrity and induces a stress response when damages occur in the outer membrane or in the peptidoglycan layer. Built around a two-component system, Rcs… read more here.
Keywords: envelope stress; igaa; distinct domains; rcs ... See more keywords
IgaA negatively regulates the Rcs Phosphorelay via contact with the RcsD Phosphotransfer Protein
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DOI: 10.1371/journal.pgen.1008610
Abstract: Two-component systems and phosphorelays play central roles in the ability of bacteria to rapidly respond to changing environments. In E. coli and related enterobacteria, the complex Rcs phosphorelay is a critical player in the bacterial… read more here.
Keywords: protein igaa; igaa negatively; rcsd; rcs phosphorelay ... See more keywords
The phosphorelay BarA/SirA activates the non-cognate regulator RcsB in Salmonella enterica
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DOI: 10.1371/journal.pgen.1008722
Abstract: To survive an environmental stress, organisms must detect the stress and mount an appropriate response. One way that bacteria do so is by phosphorelay systems that respond to a stress by activating a regulator that… read more here.
Keywords: cognate; regulator rcsb; sira; regulator ... See more keywords
Maximization of information transmission influences selection of native phosphorelay architectures
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DOI: 10.7717/peerj.11558
Abstract: Phosphorelays are signal transduction circuits that sense environmental changes and adjust cellular metabolism. Five different circuit architectures account for 99% of all phosphorelay operons annotated in over 9,000 fully sequenced genomes. Here we asked what… read more here.
Keywords: information; maximization information; selection; information transmission ... See more keywords