Conformational Changes of Glutamine 5′-Phosphoribosylpyrophosphate Amidotransferase for Two Substrates Analogue Binding: Insight from Conventional Molecular Dynamics and Accelerated Molecular Dynamics Simulations
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DOI: 10.3389/fchem.2021.640994
Abstract: Glutamine 5′-phosphoribosylpyrophosphate amidotransferase (GPATase) catalyzes the synthesis of phosphoribosylamine, pyrophosphate, and glutamate from phosphoribosylpyrophosphate, as well as glutamine at two sites (i.e., glutaminase and phosphoribosylpyrophosphate sites), through a 20 Å NH3 channel. In this study,… read more here.
Keywords: glutamine phosphoribosylpyrophosphate; molecular dynamics; conventional molecular; gpatase ... See more keywords
Corrigendum: Crystal Structure of the Chloroplastic Glutamine Phosphoribosylpyrophosphate Amidotransferase GPRAT2 From Arabidopsis thaliana
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DOI: 10.3389/fpls.2021.826504
Abstract: [This corrects the article DOI: 10.3389/fpls.2020.00157.]. read more here.
Keywords: structure chloroplastic; phosphoribosylpyrophosphate amidotransferase; crystal structure; chloroplastic glutamine ... See more keywords