Hypoxanthine‐guanine phosphoribosyltransferase is activated via positive cooperativity between guanine and IMP
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DOI: 10.1002/1873-3468.14306
Abstract: Hypoxanthine‐guanine phosphoribosyltransferase (HGPRT) is a key enzyme in the purine salvage pathway. Here, the reverse reaction of HGPRT from the thermophilic bacterium Hungateiclostridium thermocellum was studied in the presence of IMP and pyrophosphate. As for the… read more here.
Keywords: phosphoribosyltransferase activated; hypoxanthine guanine; guanine phosphoribosyltransferase; imp ... See more keywords