Articles with "phosphorothioate modified" as a keyword



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Electrochemical Biosensor Using DNA Embedded Phosphorothioate Modified RNA for Mercury Ion Determination.

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Published in 2018 at "ACS sensors"

DOI: 10.1021/acssensors.7b00892

Abstract: Mercury (Hg) and its compounds, originating from a variety of natural and anthropogenic sources, are ubiquitous in the natural environment, and cause severe environmental contamination and pose irreversible harm to human health. A fast and… read more here.

Keywords: biosensor using; modified rna; dna embedded; mercury ... See more keywords
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Phosphorothioate‑modified antisense oligonucleotides against human telomerase reverse transcriptase sensitize cancer cells to radiotherapy.

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Published in 2017 at "Molecular medicine reports"

DOI: 10.3892/mmr.2017.6778

Abstract: Emergence of resistance, unavoidable systemic toxicity and unsatisfactory efficacy arethe main obstacles for traditional cancer therapy. Combination with phosphorothioate modified antisense oligonucleotides (PS‑ASODN) against human telomerase reverse transcriptase (hTERT) may enhance the therapeutic effect of… read more here.

Keywords: telomerase; modified antisense; cancer; cell ... See more keywords