Autonomous Synthesis of Functional, Permanently Phosphorylated Proteins for Defining the Interactome of Monomeric 14-3-3ζ
Sign Up to like & getrecommendations! Published in 2023 at "ACS Central Science"
DOI: 10.1021/acscentsci.3c00191
Abstract: 14-3-3 proteins are dimeric hubs that bind hundreds of phosphorylated “clients” to regulate their function. Installing stable, functional mimics of phosphorylated amino acids into proteins offers a powerful strategy to study 14-3-3 function in cellular-like… read more here.
Keywords: synthesis functional; proteins defining; phosphorylated proteins; permanently phosphorylated ... See more keywords
A supramolecular hydrogel to boost the production of antibodies for phosphorylated proteins.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c9cc05633e
Abstract: Antibodies are widely used both in clinical practice and in research. However, the development of methods to increase the ratio of antibodies to recognize phosphorylated proteins remains challenging. In this study, we report a novel… read more here.
Keywords: antibodies phosphorylated; production antibodies; supramolecular hydrogel; phosphorylated proteins ... See more keywords
In Vitro Exposure to Glucose Alters the Expression of Phosphorylated Proteins in Platelets
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11020543
Abstract: Diabetes mellitus (DM) is a pro-thrombotic state that can potentially cause serious cardiovascular complications. Platelet hyperactivation plays an important role in these pathological processes, however there is little or no information on the effect of… read more here.
Keywords: exposure glucose; vitro exposure; phosphorylated proteins; glucose alters ... See more keywords
Phosphorylated Proteins from Serum: A Promising Potential Diagnostic Biomarker of Cancer
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232012359
Abstract: Cancer is a fatal disease worldwide. Each year ten million people are diagnosed around the world, and more than half of patients eventually die from it in many countries. A majority of cancer remains asymptomatic… read more here.
Keywords: promising potential; serum promising; proteins serum; phosphorylated proteins ... See more keywords