Articles with "phosphorylating yap" as a keyword



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FRK inhibits glioblastoma progression via phosphorylating YAP and inducing its ubiquitylation and degradation by Siah1

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Published in 2022 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noac156

Abstract: Abstract Background We previously report that yes-associated protein (YAP), the core downstream effector of Hippo pathway, promotes the malignant progression of glioblastoma (GBM). However, although classical regulatory mechanisms of YAP are well explored, how YAP… read more here.

Keywords: siah1; progression; yap inducing; frk ... See more keywords