ULK1-mediated phosphorylation of ATG16L1 promotes xenophagy, but destabilizes the ATG16L1 Crohn's mutant.
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DOI: 10.15252/embr.201846885
Abstract: Autophagy is a highly regulated catabolic pathway that is potently induced by stressors including starvation and infection. An essential component of the autophagy pathway is an ATG16L1-containing E3-like enzyme, which is responsible for lipidating LC3B… read more here.
Keywords: atg16l1; phosphorylation atg16l1; ulk1 mediated; crohn ... See more keywords