Mycobacterial Mutagenesis and Drug Resistance Are Controlled by Phosphorylation- and Cardiolipin-Mediated Inhibition of the RecA Coprotease.
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DOI: 10.1016/j.molcel.2018.07.037
Abstract: Infection with Mycobacterium tuberculosis continues to cause substantial human mortality, in part because of the emergence of antimicrobial resistance. Antimicrobial resistance in tuberculosis is solely the result of chromosomal mutations that modify drug activators or… read more here.
Keywords: resistance; phosphorylation cardiolipin; coprotease; reca ... See more keywords