IKK-mediated CYLD phosphorylation and cellular redox activity
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Medicine"
DOI: 10.1186/s10020-022-00439-y
Abstract: Oxidative stress is important in the development of obesity-related nephropathy (ORN). A causal relationship between IKK and ORN via CYLD-mediated inhibition of NRF2 has been described. However, contradictory explanations about the functioning of the mechanisms… read more here.
Keywords: redox activity; phosphorylation cellular; cellular redox; ikk mediated ... See more keywords
Lovastatin Alleviates α-Synuclein Aggregation and Phosphorylation in Cellular Models of Synucleinopathy
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2021.682320
Abstract: Parkinson’s disease (PD) is one of the most common neurodegenerative diseases. Pathologically, it is characterized by the aberrant aggregation of α-synuclein (α-syn) in neurons. Clinical evidence shows that patients with hypercholesterolemia are more likely to… read more here.
Keywords: lovastatin alleviates; aggregation; aggregation phosphorylation; cellular models ... See more keywords