BRD7 regulates the insulin-signaling pathway by increasing phosphorylation of GSK3β
Sign Up to like & getrecommendations! Published in 2017 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-017-2711-x
Abstract: Reduced hepatic expression levels of bromodomain-containing protein 7 (BRD7) have been suggested to play a role in the development of glucose intolerance in obesity. However, the molecular mechanism by which BRD7 regulates glucose metabolism has… read more here.
Keywords: brd7; signaling pathway; phosphorylation gsk3; phosphorylation ... See more keywords
Regulation of GSK3β by Ser389 Phosphorylation During Neural Development
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DOI: 10.1007/s12035-020-02147-2
Abstract: GSK3β is a constitutively active kinase that promotes cell death, which requires strict regulatory mechanisms. Although Akt-mediated phosphorylation at Ser 9 is the default mechanism to inactivate GSK3β, phosphorylation of GSK3β at Ser 389 by… read more here.
Keywords: phosphorylation gsk3; gsk3; ser 389; brain ... See more keywords