Molecular Dynamics Simulations of DNA Pol β Phosphorylation-Induced Structural Changes
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DOI: 10.1016/j.bpj.2016.11.1051
Abstract: DNA polymerase β is a 39 kDa enzyme that is a major component of Base Excision Repair in human cells. The enzyme comprises two major domains, a 31 kDa domain responsible for the polymerase activity… read more here.
Keywords: structural changes; dna polymerase; phosphorylation induced; polymerase ... See more keywords
Phosphorylation Induced Conformational Transitions in DNA Polymerase β
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DOI: 10.3389/fmolb.2022.900771
Abstract: DNA polymerase β (pol β) is a member of the X- family of DNA polymerases that catalyze the distributive addition of nucleoside triphosphates during base excision DNA repair. Previous studies showed that the enzyme was… read more here.
Keywords: phosphorylation; dna polymerase; phosphorylation induced; induced conformational ... See more keywords