Investigating Phosphorylation Patterns of the Ion Channel TRPM7 Using Multiple Extraction and Enrichment Techniques Reveals New Phosphosites
Sign Up to like & getrecommendations! Published in 2019 at "Journal of The American Society for Mass Spectrometry"
DOI: 10.1007/s13361-019-02223-5
Abstract: AbstractThe study of membrane proteins, and in particular ion channels, is crucial to understanding cellular function. Mass spectrometry-based approaches including bottom-up strategies to study membrane proteins have been successful yet still can remain challenging. In… read more here.
Keywords: trpm7; phosphorylation patterns; ion channel; patterns ion ... See more keywords
Mapping distinct vasodilator-induced phosphorylation patterns in human vascular smooth muscle: A quantitative phosphoproteomic approach
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5732062
Abstract: In vascular smooth muscle cells (VSMCs), the diffusive second messenger, 3'-5'-cyclic adenosine monophosphate (cAMP), relays crucial blood vessel-widening 'relaxation' signals from surface receptors to downstream effectors. These in turn modulate multiple proteins to relax VSMCs… read more here.
Keywords: phosphorylation patterns; camp; physiology; phosphorylation ... See more keywords