Discovery of Pyrimidine- and Coumarin-Linked Hybrid Molecules as Inducers of JNK Phosphorylation through ROS Generation in Breast Cancer Cells
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DOI: 10.3390/molecules28083450
Abstract: Human epidermal growth factor receptor 2 (HER2)-positive breast cancer exhibits early relapses, poor prognoses, and high recurrence rates. Herein, a JNK-targeting compound has been developed that may be of utility in HER2-positive mammary carcinoma. The… read more here.
Keywords: phosphorylation ros; coumarin linked; jnk phosphorylation; breast cancer ... See more keywords