Nimodipine attenuates tau phosphorylation at Ser396 via miR‐132/GSK‐3&bgr; pathway in chronic cerebral hypoperfusion rats
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2017.10.027
Abstract: ABSTRACT Chronic cerebral hypofusion (CCH) promotes hyperphosphorylation of tau proteins, a key neuropathological trait that reflects neurodegenerative disorders. Nimodipine, an L‐type calcium channel antagonist, has been reported to show neuroprotective effects. In this study, we… read more here.
Keywords: tau phosphorylation; gsk bgr; phosphorylation ser396; mir 132 ... See more keywords