Phosphorylation of serine 305 in tau inhibits aggregation
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2018.11.011
Abstract: Alzheimer's disease and other tauopathies are characterized by the brain accumulation of hyperphosphorylated aggregated tau protein forming pathological inclusions. Although elevated tau phosphorylated at many amino acid residues is a hallmark of pathological tau, some… read more here.
Keywords: aggregation; tau; aggregation phosphorylation; phosphorylation serine ... See more keywords
Paxillin phosphorylation at serine 273 and its effects on Rac, Rho and adhesion dynamics
Sign Up to like & getrecommendations! Published in 2018 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1006303
Abstract: Focal adhesions are protein complexes that anchor cells to the extracellular matrix. During migration, the growth and disassembly of these structures are spatiotemporally regulated, with new adhesions forming at the leading edge of the cell… read more here.
Keywords: phosphorylation serine; adhesion; adhesion dynamics; rac rho ... See more keywords
Role of Connexin 43 phosphorylation on Serine-368 by PKC in cardiac function and disease
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.1080131
Abstract: Intercellular communication mediated by gap junction channels and hemichannels composed of Connexin 43 (Cx43) is vital for the propagation of electrical impulses through cardiomyocytes. The carboxyl terminal tail of Cx43 undergoes various post-translational modifications including… read more here.
Keywords: cx43; phosphorylation serine; serine 368; phosphorylation ... See more keywords