Mitotic Phosphorylation of TREX1 C Terminus Disrupts TREX1 Regulation of the Oligosaccharyltransferase Complex
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DOI: 10.1016/j.celrep.2017.02.051
Abstract: SUMMARY TREX1 mutations are associated with several auto-immune and inflammatory diseases. The N-terminal DNase domain of TREX1 is important for preventing self-DNA from activating the interferon response. The C terminus of TREX1 is required for… read more here.
Keywords: mitotic phosphorylation; trex1; terminus; phosphorylation trex1 ... See more keywords